Thanks to cheap DNA sequencing, we are slowly starting to understand the incredible diversity of bacteria. I build computational tools to help us use all this data to understand how diverse bacteria work. This understanding can help us manage our environment, control the bacteria inside us, and develop new biotechnologies.
Or see publications
- The Fitness Browser: browse mutant phenotypes for ~100,000 bacterial genes
- Or use Fitness BLAST to link a gene to homologs with phenotypes
- Also see RB-TnSeq: Estimating mutant fitness by sequencing randomly barcoded transposons
- PaperBLAST: find papers about a protein or its homologs
- FastTree: evolutionary histories for big gene families